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KMID : 1155520190140010035
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Anesthesia and Pain Medicine
2019 Volume.14 No. 1 p.35 ~ p.39
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Transfusion-related acute lung injury in a parturient diagnosed with myelodysplastic syndrome - A case report -
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Sung Tae-Yun
Jee Young-Seok
Lee Seok-Jin
You Hwang-Ju
Jeong Ki-Sooon
Kang Po-Soon
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Abstract
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Transfusion-related acute lung injury (TRALI) is defined as a new episode of acute lung injury that occurs during or within 6 hours of a completed transfusion, which is one of the leading causes of transfusion-related morbidity and mortality. We present a case of TRALI in a 29-year-old parturient with myelodysplastic syndrome scheduled for cesarean section. The parturient developed hypoxemia and dyspnea after preoperative transfusion of platelets following apheresis to eliminate a unit of leucocyte in order to correct thrombocytopenia. She underwent emergent caesarean section for fetal distress. After surgery, the chest radiograph showed diffuse haziness of both lung fields. Direct and indirect antiglobulin tests were negative, and hemolytic transfusion reaction was ruled out. Pro-BNP 347.3 pg/ml also excluded transfusion-associated circulatory overload. The parturient completely recovered after oxygen support for 2 days. It is important to recognize TRALI as soon as possible to minimize perioperative morbidity and mortality.
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KEYWORD
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Cesarean section, Dyspnea, Myelodysplastic syndrome, Transfusion-related acute lung injury
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